Therefore, almost all scientific guidelines now recommend specific treatments for patients with type 2 diabetes based on CVOTs data, namely adding to metformin a SGLT-2 inhibitor or a GLP-1RA with proven CV disease benefit in patients with type 2 diabetes and CV disease, established kidney disease, or HF [7,8,9,10]
Possible side effects of orlistat (Xenical/Alli) While the active ingredient orlistat which works by inhibiting the enzymes that break down fat in the gut, preventing your body from absorbing it debuted back in 1999 to a lot of fanfare, Fishman says its become less popular for two big reasons: side effects and minimal benefits. Those side effects are mostly gastrointestinal, and can include abdominal pain in up to 30% of patients
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After obtaining the lizards DNA, Lotte Knudsen, DMSc, at Novo Nordisk developed a long-acting form of GLP-1 that became the drug that mimics the human hormone
Implications for pharma marketers and consumers: The removal of suicide warnings helps pharma marketers position GLP-1 therapies as safe, mainstream therapies for chronic conditions, just as new oral options are expected expand the market
