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The endocrinological benefits of dietary changes are reinforced by exercise when this increases insulin sensitivity, reduces visceral fat, and is a major determinant in the individuals overall well-being

In STEP 1, in a population of obese or overweight people without diabetes, those who received semaglutide 2.4 mg plus a lifestyle intervention over 68 weeks lost an average of 14.9% in bodyweight as compared with just a 2.4% reduction in the placebo plus lifestyle intervention group

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And as GLP-1 hype continued to build, thats exactly what I proclaimed to anyone around me who would listen