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Dinh Tran, MD, provides personalized, family-focused care for diagnosing and treating vitamin B12 deficiency and related conditions

At the same time, appetite changes, gastrointestinal symptoms, or impaired absorption may limit oral intakemaking repletion more challenging through diet or supplements alone

Formulations can vary based on provider recommendations and pharmacy preparation

Given that efficacy is related to trough levels, more frequent dosing may be sensible in patients with augmented renal clearance (e.g., 1 gram IV q8hrs rather than 1.5 grams q12hrs)