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Proc Am Soc Clin Oncol 23:242, 2004

The recent Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes (SELECT) trial evaluated the risk of MACE in people with overweight or obesity

Regulatory frameworks for peptide drugs have matured, providing clear pathways for development and approval

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[57] Obese patients are at high risk of developing a variety of comorbid conditions, such as CVD, gastrointestinal disorders, T2D, joint and muscular disorders, respiratory problems, and psychological issues, all of which can have a significant impact on their daily lives while also increasing their mortality risk