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Indeed, GLS inhibitors have shown promising tumor-suppressive activities in preclinical models for 968 and bis-2-(5-phenylacetamido-1,3,4-thiadiazol-2-yl)ethyl sulfide (BPTES), or even in clinical models for CB-839 [100,101]

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Food and Drug Administration 5630 Fishers Lane, Rm 1061, Rockville, MD 20852: Center for Drug Evaluation and Research (2018)

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2 Department of Biological Science, Purdue University, West Lafayette, IN, USA *These authors contributed equally to this work Abstract: Glutathione S-transferase (GST) is a Phase II metabolic enzyme that is an important facilitator of cellular detoxification

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