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The rapid symptom improvement described in a BN case report using liraglutide, with remission occurring within two weeks and maintained for five years [57], may compatible with a possible replacement-like mechanism, although this interpretation remains speculative and requires confirmation in controlled studies

A few other open-label studies, mainly from India, reported improved short-term outcomes with FMT, but the inclusion criteria and comparator arms were not consistent [89,90]

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This level of influence on cellular programming is unusual for a tripeptide and is part of why researchers have continued to study it extensively