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Gut microbiota depletion and fecal microbiota transplantation (FMT) confirmed that these beneficial effects were microbiota-dependent
A number of preformed (e.g., histamine and serotonin) and in situ (e.g., prostaglandins, leukotrienes, and platelet-activating factor [PAF]) mediators are released by inflammation cells
These ligands can be stably attached to the surface of exosomes through covalent bonds to enhance their targeting ability
& Britton, J
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