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Passive Absorption is the Key to Oral Supplementation About 1 percent of a dose of vitamin B12 can be absorbed passively by diffusion

As described above, there is compelling evidence that significant tissue-level cobalamin deficiency is present in some companion animal patients with gastrointestinal disease

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In addition, in research on aging-related muscle atrophy (sarcopenia), it can promote muscle cell proliferation and differentiation, reduce muscle cell apoptosis, and enhance muscle strength and endurance by activating the SIRT1 signaling pathway