Without GHK-Cu, repaired tissue may function temporarily but lack durability
Hepatic cytochrome P450 isoenzymes CYP1A2 and CYP3A4 mediate N-de-ethylation, so polymorphisms or competitive inhibition at these pathways (e.g., by certain antidepressants or azole antifungals) may increase systemic exposure, underscoring the importance of individualizing dosage and monitoring serum concentrations in prolonged infusions
Lpez-Garca B, Lee PH, Yamasaki K, Gallo RL
And dont forget to stop taking the supplement a week before the test, so it doesnt affect the results
65,66,67 Although the risk factors for PDPN are poorly understood, female sex, longer diabetes duration, increased neuropathy severity, renal dysfunction, higher HbA1c levels, and higher BMI have been suggested as contributing factors