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In individual immunoblotting experiments, we confirmed enrichment of mitochondrial markers and multiple proteins upregulated in response to BSO as early as 1 day after treatment (Fig

In the absence of GRX, pre-oxidized roGFP2-iL responds only slowly to injection of 2 mM GSH while the GRX1-roGFP2-iL fusion protein shows a dramatically increased reduction rate

Animal and cell studies show promise in areas like fertility and ovarian support, yet human trials remain sparse

The cells were treated with 10 mM EtGSH in FluoroBrite DMEM for 34 h, 1 mM BSO in FluoroBrite DMEM for 34 h, 1 mM H 2 O 2 for 20 min in FluoroBrite or vehicle (FluoroBrite DMEM)