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Key Results: Orforglipron led to significant weight loss: 6 mg: 5.1% 12 mg: 7.0% 36 mg: 9.6% Placebo: 2.5% All doses also resulted in improvements in HbA1c and other cardiometabolic measures

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Epidemiological and clinical factors associated with post-exertional malaise severity in patients with myalgic encephalomyelitis/chronic fatigue syndrome

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The benefits and risks of this medication should be carefully weighed on an individual basis

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