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But we need more large, good-quality studies to be sure

Most transaldolase deficient patients will be associated with dysmorphic features, congenital heart defects, and hemolytic anemia

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What they found: Darkening of existing nevi in 85 % of patients New nevi in 30 % Atypical features on dermatoscopy in 40 % Two cases of malignant melanoma in the followed cohort No evidence of a causal relationship, but associative correlation Why it matters: These are the most serious published safety data for Melanotan II