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Barrea L, Marzullo P, Muscogiuri G, et al

380 Another primary astrocytopathy linked to dysregulated iron homoeostasis is aceruloplasminemia, an autosomal recessive neurodegenerative disease caused by a loss of function mutations of the gene encoding ceruloplasmin, an enzyme that converts ferrous iron to ferric

Its selective action, without raising cortisol or prolactin levels, makes it a focus in research requiring stable hormonal response

Caspase-3 activity assay Both hepatocytes and liver tissues were lysed on ice with lysis buffer containing protease inhibitors, and the proteins were collected