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chronic liver disease and hepatitis may present with elevated levels Renal impairment : Reduced clearance can contribute to accumulation, though this is rarely clinically significant Solid tumours : Certain malignancies, particularly hepatocellular carcinoma and metastatic disease, may elevate B12 levels [3] Evidence suggests that unexplained markedly elevated B12 levels without supplementation may sometimes be associated with underlying disease

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Thereby, this study focused on BPC 157 effectiveness as a comparative link in both diseases, as far it may be indicated by the two models, cuprizone and cysteamine enema and then colon-colon anastomosis that fairly mimic corresponding human conditions, multiple sclerosis (12) and inflammatory bowel disease, colitis and colon-colon anastomosis (9)