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194,195 This may be due in part to zincs effects on T-cell populations: laboratory research has indicated zinc signaling promotes regulatory T cells and T-helper 1 (Th1) cells while zinc deficiency skews the immune response by increasing T-helper 2 (Th2) cell activity

Arch Ophthalmol 1991 Sep

Like other G protein-coupled receptors, the GLP-1R undergoes agonist-mediated endocytosis, but the functional and therapeutic consequences of modulating GLP-1R endocytic trafficking have not been clearly defined

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