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The 2024 semaglutide phase 2 RCT and the Weill Cornell cohort data are the most rigorous current evidence showing bone loss - but reasonable endocrinologists interpret even those findings with appropriate uncertainty about generalizability

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Carnitine also plays a role in metabolic regulation, detoxification, and cell membrane stabilization.[ref] This article covers: Mitochondrial energy production from long-chain fatty acids How carnitine is synthesized, including genes involved Effect on weight, mental health, immune response, and bone health Genetic changes and inborn errors of metabolism Lifehacks and solutions for optimizing carnitine levels Carnitine in Mitochondrial Energy Production: The Carnitine Shuttle Carnitine plays a specific role in mitochondrial energy production

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[10] Vallon, V., & Bakris, G