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Roles of GLP-1R signaling in immune cell biology Macrophages Macrophages are multifunctional innate immune cells known for their remarkable phenotypic and functional diversity, playing a significant role in regulating immune reactions and inflammation [78]

On the other hand, there are some antibiotics that may be associated with the development of mania, what experts have designed as antibiomania [327]

Then, in 2015, Lee and colleagues identified a previously overlooked open reading frame within the 12S ribosomal RNA gene of mtDNA and found that it encodes a functional peptide, MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) [1]