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demonstrated that urinary total (poly) phenol excretion, measured by the Folin-Ciocalteu assay, could serve as a reliable biomarker for an anti-inflammatory diet, particularly in females, supporting the inverse relationship between total polyphenol intake and inflammation (Arancibia-Riveros et al., 2023)

The table below summarises the classic dosage tiers studied during dose-ranging

However, if the side effects persist, call your doctor for medical advice

Important boundary: those are not typical cosmetic skincare ingredients, and some are discussed in contexts that go beyond everyday topical skincare

Reported incidences included nausea (5.922.2%), diarrhea (8.825.3%), vomiting (2.99.1%), and constipation (8.816.2%), with discontinuation rates reaching 19% in high-dose monthly regimens (816 mg) [62,63,64]