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in-vitro study found that berberine protected NSC34 cells from H 2 O 2 -induced cytotoxicity by reducing ROS production, restoring glutathione, and superoxide dismutase activity, and activating the production of antioxidant proteins nuclear factor erythroid 2-related factor-2 (Nrf2) and HO-1 ( Studies have found that berberine has an antidepressant effect (Figure 1)

Lowered Oxidative Stress Studies suggest that GLP-1 receptor modulation may improve the bodys oxidative balance, reducing cellular stress and protecting tissues

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the data describe an ongoing pharmacological effect, not a lasting change

This process stops the chain reaction of cellular damage before it starts