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For example, while selenium and vitamin D have shown promising results in short-term trials, their long-term impact on endocrine and metabolic parameters in PCOS remains unclear s such as diet, lifestyle, and baseline hormonal levels, which may significantly influence the effectiveness of supplementation 52

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this medical approach needs further research

Melatonin, a hormone produced by the pineal gland, functions as an antioxidant and has been shown to support immune function, scavenge free radicals, and exert cardioprotective and neuroprotective effects (Samanta, 2022)