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PRMT1 catalyzes the mono- and asymmetric dimethylation of arginine residues, thereby influencing protein function, stability, and subcellular localization [14, 15]

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The effect of DSePA administration on RP was studied by subjecting mice to thoracic irradiation (X- or -rays, 18 Gy), treating them with DSePA (2.5 mg/kg body weight for three time a week for 6 months beginning on the day of irradiation) during the post-irradiation period and monitoring the incidence of RP through immunohistochemical and CT analysis (Table 2) [61, 62]

Together, the peptides provide a dual-component system for investigating signaling interactions related to cytoskeletal regulation and extracellular matrix remodeling in experimental models

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