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SCFAs, including acetate, propionate, and butyrate, exert protective effects on kidney diseases through the modulation of inflammation and oxidative stress, primarily via the activation of G protein-coupled receptors, leading to reduced pro-inflammatory cytokine production, lowered oxidative stress markers, thereby improved renal function ( Table 1 ) [89]
Vitamin C is a potent antioxidant that correlates with reduced risk of disease and longer lifespan, likely because of its ability to reduce oxidative damage and free radicals
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10.1016/s0013-9351(03)00109-9 299 ZhangP.LokutaK
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