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Therefore, incorporating sex-based molecular and comorbidity differences into research and clinical guidelines is essential for developing safer and more personalized medical practices 108

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FDA approval and status Ozempic is primarily approved for the treatment of type 2 diabetes, cardiovascular risk reduction, and was recently approved in 2025 for preventing worsening kidney disease in patients with chronic kidney disease (CKD) and type 2 diabetes

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Self-medicating or combining prescription drugs with controlled substances without medical supervision significantly increases the risk of adverse outcomes and undermines the therapeutic goals of treatment