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The etiology of HIT is primarily related to genetic polymorphisms of DAO or HNMT, diseases associated with DAO or HNMT deficiency, dysbacteriosis, drugs that inhibit DAO activity, foods rich in histamine, foods that inhibit DAO, and foods that promote histamine release

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The IRB should not consider possible long-range effects of applying knowledge gained in the research (for example, the possible effects of the research on public policy) as among those research risks that fall within the purview of its responsibility

Del Buono et al., Tendinopathy and inflammation: some truths, International journal of immunopathology and pharmacology 24, 1 Suppl 2 (2011): 45

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