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He presented with an intra-oral brown macular lesion on the left buccal mucosa with a duration of one and a half months

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Based on topical glutathione trials, visible changes in skin lightness (L* values) appeared by around 8-10 weeks

doi: 10.1186/s13054-022-04090-1 Liu XW, Wang CD

[1] Sermorelin occupies a second-line or adjunctive position in practices where pituitary reserve testing suggests partial deficiency or where the prescriber determines sermorelin is appropriate after a documented clinical evaluation