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But one of the things that we've been interested in is these cells are part of an interconnected network and our lab has been interested in the channels that the cells use to talk to one another

In a 2023 paper published in the Annals of the Rheumatic Diseases, Zhu and colleagues identified individuals with knee OA and comorbid type 2 diabetes mellitus from a cohort of more than 40,000 participants in the Shanghai Osteoarthritis Cohort study

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In the duodenum, pancreatic enzymes degrade the R-protein-B12 complexes, freeing B12 to bind with intrinsic factor (IF) , a glycoprotein produced by gastric parietal cells in the stomach lining

Avoiding high-fat, spicy, or heavily seasoned foods may also help, as these can exacerbate gastrointestinal symptoms