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Whether microdosing any GLP-1 agonist produces clinically meaningful results remains an open question in the research literature

The epithelium of the non-inflamed ileum shows a normal permeability to ions and a normal paracellular permeability to 51 Cr-EDTA as compared to controls (119, 120) but is more susceptible to a challenge with sodium caprate indicating that TJs in the non-inflamed ileum of CD are more reactive to luminal stimuli contributing to the development of mucosal inflammation (120)

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These anti-inflammatory effects help create the conditions necessary for tissue repair rather than continued degradation