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Modern GLP-1 agonists amplify and prolong the signal from our native GLP-1

Intriguingly, a post hoc analysis of a phase 2 clinical trial revealed that dulaglutide treatment resulted in reductions in apoC-III and apoB levels without impacting serum LPL level, whereas treatment with tirzepatide showed a dose-dependent increase in serum LPL activity while concurrently reducing apoC-III and apoB levels (180)

Light alcohol may be tolerated, but it can worsen nausea or slow weight loss

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DOI.org (Crossref) , Brierley, Daniel I., et al