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a set of mental skills that help people manage everyday tasks and solve problems requiring planning, flexibility in thinking and self-control (assessed by the Tower of London task) (F = 4.504, p = 0.015)
Brim H, Taylor J, Abbas M, Vilmenay K, Daremipouran M, Varma S, Lee E, Pace B, Song-Naba WL, Gupta K, Nekhai S, ONeil P, Ashktorab H (2021) The gut microbiome in sickle cell disease: characterization and potential implications
Its approval was supported by data from the Phase III CAHtalyst study, which demonstrated that Crenessity significantly lowered androstenedione concentrations in both adult and pediatric patients, allowing them to taper glucocorticoid doses without affecting treatment efficacy
doi: 10.1038/s41586-021-03819-2 167 KamphuisW.MiddeldorpJ.KooijmanL.SluijsJ
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