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Works best with Exercise: A randomized clinical trial found that GLP-1 RAs work best for weight loss when combined with exercise

Dose reduction provides a less intense but potentially useful partial reset

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(source: sec.gov) January 2026 : Novo Nordisk announced the broad availability of the Wegovy pill across America

In common use, though, people say GLP-1 to mean FDA-approved incretin drugs for weight/diabetes, and peptide therapy to mean other wellness-oriented peptides used off-label for recovery, sleep, and healthy aging