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Nrf2 is involved in not only the regulation of GSH synthesis and reduction via upgrading some enzymes and proteins (SLC7A11, GCLM, GCLC, GR) but also the activation of GSH-dependent antioxidant enzymes (GPX, GST) [200, 201]

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Glycosaminoglycan and proteoglycan biosynthesis pathway investigation

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Therefore, it is vital to investigate and incorporate sensitive IR probes into OPTIR systems that enable background-free detection of metabolic products