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That description is broadly correct but incomplete

These cytokines impair beta cell function, lowering insulin secretion (Lontchi-Yimagou 2013

Furthermore, the release of sDPP4 was elevated in adipose tissue explants of obese patients compared to lean controls and correlates with various classical markers of the metabolic syndrome, namely BMI, waist circumference, plasma triglycerides, and HOMA as an index of IR, as well as with fat cell volume and the adipokine leptin (4, 5)

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The research and development of new pharmaceuticals is increasingly an international affair, something that recent discussion about how tariffs might affect drug prices has made very clear