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In this experiment, although the spleen, thymus, and liver indexes of mice in NM group did not exhibit significant change, the spleen index displayed a declining trend

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This is the case in humans and most other complex species (Wilding, 2001)

J Neurochem 108 (Suppl 1):73 Evans TA, Siedlak S, Lu L, Fu X, Wang Z, McGinnis W R, Fakhoury E, Castellani RJ, Hazen SL, Walsh WJ, Lewis AT, Salomon RG, Smith MA, Perry G, Zhu X (2008) The autistic phenotype exhibits a remarkably localized modification of brain protein by products of free radical-induced lipid oxidation