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However, chronic, recurring, or severe spasms deserve professional evaluation when any of the following apply: Spasms occur multiple times per week without obvious provocation Pain is severe or doesnt respond to heat, hydration, or stretching within 2448 hours Spasms affect multiple body areas simultaneously (whole-body muscle cramps throughout the body) There is associated muscle weakness, numbness, tingling, or loss of coordination Spasms follow a recent surgery, injury, or new medication You notice muscle wasting (atrophy) in the affected limb Spasms are waking you from sleep repeatedly Which Doctor to See Start with your primary care physician (PCP)

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Limitations in Clinical Evidence and Trial Design The current orthopaedic literature on peptides is dominated by animal models, small prospective cohorts, and case series, with very limited RCTs