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The data are presented as mean SEM

This South-Korea based pharma was a major leader in GLP-1 development during the 2010s, alongside Eli Lilly and Novo Nordisk, developing three different GLP-1 drugs: Efpeglenatide, a once-weekly GLP-1 agonist, Efinopegdutide, a once-weekly GLP-1/Glucagon dual agonist, and HM15211, a once-weekly GLP-1/GIP/Glucagon triple agonist

identified eight novel potential GPX4 activators and determined that compound 1d4 is the most potent allosteric activator of GPX4, effectively inhibiting ferroptosis in HT-1080 fibrosarcoma cells [328]

Bull Chem Soc Ethiop