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When and How to Discuss GLP-1 Options with Your Provider Post-Cholecystectomy Before considering any GLP-1 medication post-cholecystectomy, your provider should assess: time since surgery (typically 6 months preferred for metabolic stabilization), current gastrointestinal symptom severity, baseline medication tolerances, nutrient absorption status, and metabolic goals

Ozempic can be used alone or in combination with other antidiabetic medications, depending on individual treatment needs and healthcare providers recommendations

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There are some studies using lactisole, a sweet taste receptor antagonist, that have shown reduced GLP-1 and PYY secretion in response to glucose, but no effect on CCK release (6870)