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The activity of e-GST has been compared with the level of e-CAT, an enzyme often considered a biosensor of oxidative stress (Figure 1c)

doi: 10.1099/vir.0.052910-0 39 De WildeA

One of the main actions of berberine is to activate an enzyme inside cells called AMP-activated protein kinase (AMPK), according to some animal studies ( AMPK plays a key role in regulating metabolism and energy levels and is found in cells throughout your body ( Berberine also affects other molecules inside cells and may even affect which genes are turned on or off

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