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Tirzepatide may also become an important pharmacological tool for the treatment of obesity if data from the SURMOUNT-1 trial are confirmed in other clinical studies (82)

These medications can lead to a significant and clinically meaningful reduction in body weight when used in conjunction with lifestyle changes

Your GP can also provide evidence-based guidance on lifestyle modifications that naturally support incretin function, such as: Adopting a diet rich in whole foods, vegetables, and dietary fibre Achieving and maintaining a healthy body weight Engaging in regular physical activity Optimising sleep and stress management These interventions have robust evidence for improving metabolic health and may naturally enhance GLP-1 and GIP secretion without the need for supplements

Insurance-reimbursed care becomes more important when treatment costs rise or long-term use is expected

The only side effect Ive experienced is a little acid reflux, but its mild and goes away quickly