284 Jun, J

If cholelithiasis is suspected, gallbladder diagnostic studies and appropriate clinical follow-up are indicated Tell your healthcare provider right away if you get symptoms of gallbladder problems which may include: pain in your upper stomach (abdomen) fever yellowing of skin or eyes (jaundice) clay-colored stools Low Blood Sugar (Hypoglycemia) Your risk for getting low blood sugar may be higher if you use Zepbound with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin Signs and symptoms of low blood sugar may include: dizziness or light-headedness sweating confusion or drowsiness headache blurred vision slurred speech shakiness fast heartbeat anxiety, irritability, or mood changes hunger weakness feeling jittery Concomitant use with an insulin secretagogue (e.g., sulfonylurea) or insulin may increase the risk of hypoglycemia, including severe hypoglycemia The risk of hypoglycemia may be lowered by reducing the dose of sulfonylurea (or other concomitantly administered insulin secretagogue) or insulin

This study used a flexible protocol, like the REDEFINE 1 study, which allows patients to modify their dosages during the trial
It's FDA approved for two main uses: chronic weight management in adults with obesity (or overweight plus a weight-related condition), and moderate to severe obstructive sleep apnea (OSA) in adults with obesity
From there, maintenance is typically one injection every four to twelve weeks depending on diet, absorption and how the response holds