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If you have Leber's hereditary optic neuropathy, you should avoid cyanocobalamin forms of B12

[2] [15] Nitrous oxide misuse is an increasingly recognised cause of functional B12 deficiency and should be considered in relevant cases

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Other herbivores obtain low levels of B12 in their diets through soil and faeces, which also contain B12-producing microorganisms

If you experience suspected adverse effects from vitamin B12 medicines, report them to the MHRA Yellow Card scheme