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Silent information regulator factor 2-related enzyme 1 (sirtuin 1/Sirt1), a nicotinamide adenine dinucleotide-dependent protein deacetylase, can modulate a wide range of biological processes, including oxidative stress, inflammation, aging, apoptosis and autophagy [5]

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These cytokines are markers of chronic low-grade inflammation, the kind associated with accelerated biological aging, cardiovascular disease, neurodegeneration, and metabolic syndrome