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Pro-inflammatory signaling and Ca 2+ overload can activate kinases that phosphorylate DRP1 and other fission-related proteins, thereby promoting mitochondrial fragmentation, m loss, and increased ROS generation ( The interaction between mitochondria and the cytoskeleton also influences the spatial organization of other key processes in AP, including autophagosome trafficking, lysosomal fusion, and immune cell recruitment to the injured pancreas

supports barrier

Statistical significance was assessed using two-tailed unpaired t-tests with false discovery rate (FDR) correction using the two-stage step-up method of Benjamini, Krieger and Yekutieli (Q = 1%)

Progress in Retinal and Eye Research, 92:101117

Gut and Liver , 2019