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Although GLP-1 medications have complex dosing schedules, you can consider switching between GLP-1 medications if you experience intolerable side effects with your current medication, do not get significant results, or due to a drug shortage

Side effects are typically mild and improve over time

Concomitant administration of glimepiride tablets (4 mg once daily) did not alter the pharmacokinetic characteristics of R- and S-warfarin enantiomers following administration of a single dose (25 mg) of racemic warfarin to healthy subjects

Citation: Chowdhury WK, Arbee S, Debnath S, Alija T, Khan A, et al