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300a-7, 42 U.S.C

When to seek medical advice: Persistent or worsening injection site reactions (increasing redness, warmth, or discharge suggesting infection) Severe or persistent headaches Chest pain or palpitations Unexplained muscle weakness or cramps New or worsening neurological symptoms despite treatment Unexpected bleeding or bruising For non-emergency concerns, contact your GP or NHS 111

For some people these changes are among the first noticeable signs, though mood symptoms can have many causes and should be evaluated by a professional

Ensure that you use it before the expiry date mentioned on the packaging