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Rather than using the standard 0.25 to 0.5 mg daily dose, micro-dosing protocols employ significantly smaller amounts, typically ranging from 0.1 to 0.15 mg per administration

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Inflammatory cytokines adversely affect different components of the central nervous system (CNS) and peripheral nervous system (PNS), which may, in turn, lead to degeneration of neurons and microglial cells, increased BBB permeability, as well as prolonged levels of microglial activation, which impairs neurogenesis (36, 37)

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