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Silencing of miR122 has been shown to upregulate CAT-1 ( SLC7A1 ) expression, and subsequently increase arginine uptake to maintain large intracellular arginine pools for nitric oxide (NO) synthesis, resulting in increased resistance to the multi-kinase inhibitor sorafenib (Kishikawa et al., 2015)

Information was retrieved from RefSeq ( [30] and Uniprot ( [31] databases (TIFF 128 kb) Supplementary Figure 3 (download TIF Confirmed transcript variants of GSTO1, GSTO2, GSTP1 and GSTS1

10.1016/0005-2744(80)90004-2 37 LahtiP

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