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Current drugs like Wegovy mainly target GLP-1, while Zepbound targets GLP-1 and GIP

In mammals, LC treatment activated the main marker proteins of mitophagy, such as PINK1, Parkin, BCL2/adenovirus E1B 19 kDa protein interacting protein 3 (BNIP-3) and microtubule-associated protein 1 light chain 3 B-II (LC3B-II) (Reference Sabry, Ahmed and Maksoud73,Reference Choi, Ohn and Jung75) , and decreased hepatic 8-hydroxydeoxyguanosine in rats (Reference Chang, Nishikawa and Nishiguchi79)

Nauck M, Stckmann F, Ebert R, Creutzfeldt W

Graphene oxide quantum dots inhibited the expression of -synuclein, which is linked to the neuropathology and neurotoxicity of Parkinsons disease

Plasma insulin (ng/mL) was assessed using a wide-range Ultra Sensitive Mouse Insulin ELISA Kit (Crystal Chem, Cat #90080)