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Next, considering the duration of drug administration, GLP-1RA has a diminished effect after chronic administration, also known as tachyphylaxis, although the mechanism of tachyphylaxis is currently unclear

Combined therapeutic strategies that target mitophagy may enhance the efficacy of chemotherapeutic agents like gemcitabine and paclitaxel, potentially extending the survival of PDAC patients [17, 18]

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Conclusion Micro-dosing GLP-1 medications represents a groundbreaking advancement in safe weight management solutions