There is no published human safety or efficacy data, no reproductive- or developmental-toxicology research, no studies in hepatic or renal impairment, and no drug-interaction studies
Eosinophil granule contents, such as major basic protein (MBP), play a large role in the hyperreactive and pro-inflammatory airway of asthma as the contents are toxic to both pathogens and host cells, and higher eosinophil counts are related to frequency of exacerbations (Dunican et al., 2018a
In the present study, elevated PGA levels were observed among 89% of symptomatic TTR-V30M patients and in 63% of asymptomatic carriers relative to the median of healthy controls (Table 1)
For example, in people with asthma, an obstructive lung disease that affects nearly 300 million people globally [144], the effect of cannabis on lung function is contradictory
Many patients experience an average weight loss of 10% to 18% of their starting body weight, and some lose 15% to 21% of their body weight over 68 weeks, depending in part on starting weight