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In addition, the absolute abundance of the gut microbiota doubled by HFD intervention (51), which indicated that although the relative abundance of Bacteroidetes was reduced, the total number may not have changed significantly

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Glutathione is present in every cell of the body, and the depletion of glutathione is noted in a wide range of medical conditions

The RBD region on the S1 subunit recognizes anchor point(s) on the host cell surface, whereas the S2 subunit facilitates fusion of viral envelope with the host cell membrane after proteolytic cleavage of S1/S2 site to mediate viral entry 68,69

Moreover, nonsteroidal anti-inflammatory drugs (NSAIDs), prototypic inhibitors of cyclooxygenase (COX) activity and PGE2 production, can trigger or worsen the disease (51, 52)